ALLOBLAST (Allogeneic Fibroblast) is a registered trademark presented for the first time in Turkey by DOKU BIOTECHNOLOGY STEM CELL, BIONBANK AND TISSUE ENGINEERING and is introduced to physicians with the solution partnership of GENESİS BIOMEDICAL INC. Some copy, imitation, etc. products offered in the market as allogeneic fibroblasts have nothing to do with the brands/products offered by our organization or our solution partners.
ALLOBLAST® is derived from the foreskins of newborn boys. On average, one in every 500 foreskins can be considered to fulfill the criteria to be a healthy donor. For this reason, not every newborn is considered a suitable donor for ALLOBLAST production. In addition, thanks to the high-tech production techniques of our center, ALLOBLAST can be produced for 1000s of people from the foreskin of only 1 suitable donor. Before the reliability of the ALLOBLAST source is confirmed, clinical product production processes are not started and the tissues are destroyed. Records are kept for sharing with the Ministry of Health.
By making an examination appointment with your doctor, you will be interviewed about your aesthetic / cosmetic purpose or any dermatological problem and a decision will be made together with your physician in line with your suitability for ALLOBLAST application.
Prior to ALLOBLAST ® applications, the Cellular Product Order Form and Informed Consent Form are read, any unclear issues are investigated, detailed information is obtained from the physician, and the product order is sent to our center through your physician. At least one day before the day the application is planned to be performed, the order is sent to our center via Whatsapp, Mobile Call or e-mail. In our facility, which has received GMP, Human Tissue and Cell Product Production and Banking approvals from the Ministry of Health, the required amount of billions of allogeneic fibroblast cells cryopreserved in a high-tech nitrogen tank are taken and prepared sterile for you. This process goes through the quality control processes specified by the Ministry of Health and the European Standard, which are specific to the ALLOBLAST production technique.
The person comes to the clinic; the skin is numbed with topical anesthetic creams. ALLOBLAST® 27G-30G is drawn into sterile syringes and injected into the required area. ALLOBLAST® application consists of a single session. If additional sessions are requested in the same area, a break of at least 3 weeks should be taken.
*After the application of ALLOBLAST, while the skin shines, brightens and looks lively, improvement in fine lines and color tone differences, increase in moisture capacity at the end of the 1st month, a noticeable reduction in skin wrinkles, skin tightening and tightening against gravity can be observed at the end of the 3rd month. It has been shown in scientific and clinical studies that the effect can last for at least 1 year and up to 5 years.
* Expressed in line with the feedback of 500+ doctors and 500+ people who had the application.
It consists of pure newborn fibroblast cells that are healthy, young and resistant to adverse metabolic stresses.
(1) Expressed in comparison to autologous fibroblasts based on laboratory tests.
(2) Neonatal fibroblasts do not elicit immune responses when they are obtained from specific donors (selection), at specific stages and can be produced under specific production and quality criteria.
(3) Pure neonatal fibroblasts contain bioactive molecules produced by the cells and isotonic saline as a carrier.
It is one of the cellular treatment methods approved by the FDA and EMA (European Medicines Agency) in the world.
Collagen production is 4 times higher than fibroblasts in their 40s.(1)
Permanent and longer regenerative effect is targeted thanks to long telomeres.
It is produced in a GMP approved stem cell, biobank and tissue engineering center with the permission of the Ministry of Health and is tested and approved.
It can be applied to dermal areas all over the body, including around the eyes and genital area.
It can be applied the next day only if requested 24 hours in advance (same day for Ankara).
The recommended application is a single session, but multiple sessions can also be performed with the doctor’s approval.
There is no need for serology tests, biopsy and blood sampling, so no time is lost with production processes that take at least 4 weeks.
Does not cause allergy or immune reaction. (2)
It does not contain Botox or any filler components, it is a pure cell solution. (3)
It does not produce an appearance that may cause changes in mimicry or facial expression.
ALLOBLAST is an application based on increasing the concentration of fibroblasts that produce extracellular matrix proteins known to be effective in dermal regeneration, especially collagen and elastin, by placing them on the skin. However, it should be known that the person’s condition, age, genetic predispositions, lifestyle, food consumption habits and many other factors will affect the success of this application and the application decision should be made after a doctor’s evaluation.
All of the information on the website is for informational purposes. In addition to the explanations, a reference list of scientific and clinical studies is included on the pages. The use of any product or products is decided by the person who wants to have cellular application and the doctor who will perform the application.
Doku Biotechnology Stem Cell, Biobank and Tissue Engineering Center, as a facility authorized by the Ministry of Health and having permission documents in this context, is obliged to produce cellular products in accordance with national/international norms and GMP requirements, to perform quality analyzes, to store and to deliver the cellular product to the doctor who requests and consents to perform the application for the recipient. The application process must be performed by the physician under appropriate clinical conditions, with the technique and duration appropriate to the indication based on scientific and clinical data in the world, within the framework of the law and professional ethical rules.